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DeCS
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Descriptor English:
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Genes, Retinoblastoma
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Descriptor Spanish:
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Genes de Retinoblastoma
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Descriptor Portuguese:
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Genes do Retinoblastoma
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Synonyms English:
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Gene, Rb
Gene, Retinoblastoma
Genes, Rb
Rb Gene
Rb Genes
Retinoblastoma Gene
Retinoblastoma Genes
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Tree Number:
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G05.360.340.024.340.375.249.400
G05.360.340.024.340.415.400.400
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Definition English:
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Tumor suppressor genes located on human chromosome 13 in the region 13q14 and coding for a family of phosphoproteins with molecular weights ranging from 104 kDa to 115 kDa. One copy of the wild-type Rb gene is necessary for normal retinal development. Loss or inactivation of both alleles at this locus results in retinoblastoma. |
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See Related English:
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Retinoblastoma
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History Note English:
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91
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Allowable Qualifiers English:
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Record Number:
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28960
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Unique Identifier:
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D016161
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Occurrence in VHL:
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Similar:
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DeCS
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